Niacin

What does this medication do?
Niacin, also known as nicotinic acid, is a form of vitamin B, which should only be taken as a cholesterol-lowering medication when prescribed by your doctor.

How does it work?
It works by slowing the livers production of LDL (the bad) cholesterol. It also raises HDL (the good) cholesterol.

How should I take it?
Niacin should be taken with food. Niacin may produce some side effects like flushing or itching, but these decrease after two to six weeks if you continue to take niacin. For this reason, your doctor will probably start you at a low dose and gradually increase it. However, if you stop taking niacin for a period of time, you should make sure you start back at the dose your started with at the beginning (to avoid severe flushing). Some doctors recommend taking ASA 325mg 30 to 60 minutes before your dose to reduce flushing. Always talk to your doctor or pharmacist about how and when to take your medication.

What if I am taking other medicines?
Always tell your doctor about any other medication including prescription, non-prescription, over-the-counter or natural health products (vitamins and minerals, herbal remedies, homeopathic medicines, traditional medicines such as traditional Chinese medicines, probiotics and other products like amino acids and essential fatty acids).

What else should I tell my doctor?
Inform your doctor if you have liver, gallbladder or gout. If you have diabetes, niacin may worsen your blood sugar control (this may need to be monitored).

What are some common side effects?
Some common side effects include flushing (redness or a burning or itching sensation), dry skin or a rash, upset stomach, diarrhea, headaches. Most of these side effects decrease after continuing to take the drug for two to six weeks. Talk to your doctor or pharmacist if you experience any side effects.

Lifestyle changes
Eating a healthy diet that is lower in fat, especially saturated and trans fats, being smoke free, limiting alcohol use, being physically active and reducing stress are also important in lowering the risk of heart disease. Talk to your health-care practitioner about how you can achieve these lifestyle changes.

Where can I get more information?
For warnings, recalls and other clinical drug information:

  1. Health Canada Drugs and Health Products http://www.hc-sc.gc.ca/dhp-mps/prodpharma/index_e.html
  2. Drugs and Health Products: Advisories, Warnings and Recalls http://www.hc-sc.gc.ca/dhp-mps/medeff/advisories-avis/index_e.html

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